Nicotinic receptor-mediated catecholamine secretion from individual chromaffin cells. Chemical evidence for exocytosis.

doi:10.1016/S0021-9258(18)77173-1

Journal of Biological Chemistry

Volume 265, Issue 25, 5 September 1990, Pages 14736-14737

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Nicotinic receptor-mediated secretion of catecholamines from individual cultured bovine adrenal medullary chromaffin cells was measured and characterized with a voltametric microelectrode placed adjacent to the cells. Nicotine-induced secretion is associated with a large increase in chemical spikes that is temporally resolved into the apparent secretion of discrete packets of attomole quantities of easily oxidized molecules. These data are consistent with direct chemical measurement of single exocytotic events.

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Cited by (0)

[1] 1
Ceccarelli B., Hurlbut W.P.
Physiol. Rev., 60 (1980), pp. 396-441
View at publisher
Crossref View in Scopus Google Scholar

[2] 2
Katz B., Miledi R.
J. Physiol. (Load.), 189 (1967), pp. 535-544
View at publisherCrossref View in Scopus Google Scholar

[3] 3
Hume R.I., Role L.W., Fischbach G.D.
Nature, 305 (1983), pp. 632-634
View at publisher
Crossref View in Scopus Google Scholar

[4] 4
Young S.H., Poo M.M.
Nature, 305 (1983), pp. 634-637
View at publisher
Crossref View in Scopus Google Scholar

[5] 5
Douglas W.W.
Br. J. Pharmacol., 34 (1968), pp. 452-474
Google Scholar

[6] 6
Viveros O.H., Arqueros L., Kirshner N.
Science, 165 (1969), pp. 911-913
View at publisher
Crossref View in Scopus Google Scholar

[7] 7
Viveros O.H.
Blaschko A., Smith A.D. (Eds.), Hand book of Physiology, Section on Endocrinology, 6, American Physiological Society, Washington, D. C. (1975), pp. 389-426
Google Scholar

[8] 8
Neher E., Marty A.
Proc. Natl. Acad. Sci. U. S. A., 79 (1982), pp. 6712-6716
Finding PDF…Crossref View in Scopus Google Scholar

[9] 9
Cheek T.R., Jackson T.R., O'Sullivan A.J., Moreton R.B., Berridge M.J., Burgoyne R.D.
J. Cell Biol., 109 (1989), pp. 1219-1227
View in Scopus Google Scholar

[10] 10
Wilson S.P., Viveros O.H.
Exp. Cell Res., 133 (1981), pp. 159-169
View PDF View article View in Scopus Google Scholar

[11] 11
Menniti F.S., Knoth J., Diliberto E.J. Jr.
J. Biol. Chem., 261 (1986), pp. 16901-16908
View PDF View article View in Scopus Google Scholar

[12] 12
Kristensen E.W., Kuhr W.G., Wightman R.M.
Anal. Chem., 59 (1987), pp. 1752-1757
Finding PDF…Crossref Google Scholar

[13] 13
Baur J.W., Kristensen E.W., May L.J., Wiedemann D.J., Wightman R.M.
Anal. Chem., 60 (1988), pp. 1268-1272
Finding PDF…Crossref View in Scopus Google Scholar

[14] 14
Boska P., Livett B.G.
J. Neurochem., 42 (1984), pp. 607-617
Google Scholar

[15] 15
Kirkpatrick D.L., et al.
J. Neurochem., 38 (1982), pp. 427-435
Google Scholar

[16] 16
Holz R.W., Senter R.Y., Frye R.A.
J. Neurochem., 39 (1982), pp. 635-646
Finding PDF…Crossref View in Scopus Google Scholar

[17] 17
Kidokoro Y.
J. Physiol. (Lond.), 324 (1982), pp. 203-220
Finding PDF…Crossref View in Scopus Google Scholar

[18] 18
Nordmann J.J.
J. Neurochem., 42 (1984), pp. 434-437
Crossref View in Scopus Google Scholar

[19] 19
Phillips J.H.
Neuroscience, 7 (1982), pp. 1595-1609
View PDF View article View in Scopus Google Scholar

Journal of Biological Chemistry

Journal ArticleNicotinic receptor-mediated catecholamine secretion from individual chromaffin cells. Chemical evidence for exocytosis.

References

Journal Article
Nicotinic receptor-mediated catecholamine secretion from individual chromaffin cells. Chemical evidence for exocytosis.